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Title:Special Topic( Control Engineering Applications)

Selim Hacısalihzade
Class hours: ThThF 565


After completing the course successfully, the student should have a basic understanding of various medical questions and be able to offer viable control engineering solutions to medical problems in collaboration with physicians.



  • 1.    Introduction to therapeutic situations posed as control problems with systems and signals refresher (Therapeutic situations as feed-back loops; definitions of systems and signals; various stability definitions; mathematical modelling in time and frequency domains; open loop and closed loop control)
  •     The human operator (Manual control; early models of the human operator; pursuit tracking)
  •     Depth of anaesthesia control I (Anaesthesia preliminaries; measuring depth of anaesthesia; fuzzy sets refresher; fuzzy control refresher; fuzzy control of depth of anaesthesia)
  •     Depth of anaesthesia control II (Rule based control; knowledge based control; intelligent control of depth of anaesthesia)
  •     Drug administration and dosage optimisation (Pharmacokinetics; multiple dosage problem; analytical solutions; numerical solutions of the multiple dosage problem with linear programming and cyclic coordinate search methods; Prony algorithm) 
  •     Measuring Parkinson symptoms (Clinical rating scales; quantitative assessment of the neurological function; PC-based methods; signal analysis and evaluation)
  •     Dosage optimisation in Parkinson’s disease (Mathematical problem; numerical solutions; clinical applications)
  •     Discussion of term projects
  •     Closed loop control of blood glucose in diabetes (Blood glucose measurement with invasive and non-invasive techniques; intrinsic blood glucose regulation; control algorithms with and without models; a closed loop control apparatus) 
  •     Optimal management of thyroid disease (Simple endocrine model; dynamics of hormones in hypothyroid patients; optimal control in clinical endocrinology) 
  •     Vestibular and vestibulo-ocular control systems (Physiology and anatomy; saccadic eye movements; smooth pursuit system; vestibulo-ocular reflex )
  •     Standing and walking (The triple pendulum model; the hip; the knee; the ankle; stance and gait control; disturbance models)
  •     Overview and recapitulation


Basic control engineering courses
Linear systems



Boğaziçi Üniversitesi - Elektrik ve Elektronik Mühendisliği Bölümü

34342 - Bebek / İSTANBUL

Tel: +90 212 359 64 14
Fax: +90 212 287 24 65







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